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PCORI Funding gaps in patient-centered outcomes research and comparative clinical effectiveness

09 May 2019 10:23 AM | NAMEC Staff (Administrator)

Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement (PFA), PCORI aims to fund studies that address high-priority methodological gaps in patient-centered outcomes research (PCOR) and comparative clinical effectiveness research (CER). 

Letters of Intent are due Wednesday, May 29, 2019, by 5:00 p.m. ET.

Those selected to submit a full application will be notified by Monday, June 24, 2019.

Full applications will be due Wednesday, September 4, 2019, by 5:00 p.m. ET.

All of the bullet points below are available - including to submit your application - at this link

Applicant Resources

Write Your LOI

  • Methods PFA
  • Methods Application Guidelines
  • Methods LOI Template
  • Sample Methods LOI Template
  • Applicant FAQs
  • Methods PFA FAQs
  • PCORI Online: Pre-Award User Guide for Research Awards
  • Tips for Preparing a Responsive Letter of Intent (LOI)

Submit Your Application

  • Methods PFA
  • Methods Application Guidelines
  • Methods Application Checklist
  • Applicant FAQs
  • Methods PFA FAQs
  • PCORI Online: Pre-Award User Guide for Research Awards

Required Application Templates

  • People and Places Template
  • Leadership Plan Template (Only required if proposed project is dual-PI)
  • Methods Research Plan Template
  • Methodology Standards Checklist
  • Methods Milestones Template
  • Subcontractor Detailed Budget Template
  • Budget Justification Template
  • Letters of Support Table

If you are Resubmitting Your Application

  • Resubmission Letter Template

Additional Applicant Resources

  • PCORI Methodology Report and Standards
  • Policy on Submission of Research Contract Applications
  • Glossary
  • Ambassador Center
  • Engagement Rubric
  • Engagement in Research
  • Budgeting for Engagement Activities
  • Compensation Framework
  • Cost Principles: Description of Allowable Direct Costs under a PCORI Award
  • PCORI Merit Review Criteria
  • Standard Contract for Funded Research Projects

FROM PCORI: 

What & Who We Fund

Research Focus

Comparative Clinical Effectiveness Research (CER)

Studies that compare outcomes to determine the effectiveness, including risks and benefits, of two or more approaches to health care

CER Methods and Infrastructure

Studies to improve the methods available for patient-centered CER

Development of a large, highly representative electronic-data infrastructure, called PCORnet, for improving the conduct of patient-centered CER

Conditions Studied

We pay particular attention to:

  • Conditions that affect large numbers of people across a range of populations
  • Conditions that place a heavy burden on individuals, families, specific populations, and society
  • Rare diseases, which are difficult to study

Populations of Interest

We pay particular attention to a number of populations in making research funding decisions:

  • Racial and ethnic minorities
  • Older adults
  • Low-income
  • Residents of rural areas
  • Women
  • Children
  • Individuals with special healthcare needs, including individuals with disabilities, individuals with multiple chronic diseases, individuals with rare diseases, and individuals whose genetic makeup affects their medical outcomes
  • Patients with low health literacy/numeracy and limited English proficiency
  • Lesbian, gay, bisexual, transgender (LGBT) persons
  • Veterans and members of the armed forces and their families

Eligibility

Private Sector

  • Nonprofit research organizations
  • For-profit research organizations

Public Sector

  • Universities and colleges
  • Hospitals and healthcare systems
  • Laboratories and manufacturers
  • Units of state, local, or federal government

US Organizations

Must be recognized by the Internal Revenue Service

Foreign Organizations and Nondomestic Components of US Organizations

May apply if:

  • There is demonstrable benefit to the US healthcare system, and the essential scientific needs will be met by conducting the study outside the United States or having the study conducted by non-US research organizations
  • US efforts in the area of patient-centered research can be clearly shown, and the engagement plans include US patients and stakeholders, and are relevant to US healthcare system

Individuals: Not permitted to apply


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